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Usa300 clone

04.11.2020
Wickizer39401

Since 2001, a dramatic increase in methicillin-resistant Staphylococcus aureus (MRSA) infections has been observed in the United States, mostly related to emergence of the USA300 clone in the community and subsequently in hospitals (2,3). Residents of long-term care facilities (LTCFs) are at risk for colonization with antimicrobial drug–resistant bacteria, including MRSA. The USA300 North American epidemic (USA300-NAE) clone of methicillin-resistant Staphylococcus aureus has caused a wave of severe skin and soft tissue infections in the United States since it emerged in the early 2000s, but its geographic origin is obscure. Here we use the population genomic signatures expected from the serial founder effects of a geographic range expansion to infer the origin of USA300-NAE and identify polymorphisms associated with its spread. BACKGROUND: USA300, a clone of meticillin-resistant Staphylococcus aureus, is a major source of community-acquired infections in the USA, Canada, and Europe. Our aim was to sequence its genome and compare it with those of other strains of S aureus to try to identify genes responsible for its distinctive epidemiological and virulence properties. The community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) epidemic in the United States is largely attributable to the meteoric rise of a single clone, referred to as USA300. This strain not only spread across the United States in just a few years to become the predominant cause of staphylococcal disease, but it also appears to have increased the overall number of skin and soft-tissue infections (SSTIs), increasing the overall disease burden.

25 Dec 2013 A considerable difference exists among similar and various clone types After 2000, the USA300 clone (carrying the SCCmec IV and PVL loci) 

BACKGROUND: USA300, a clone of meticillin-resistant Staphylococcus aureus, is a major source of community-acquired infections in the USA, Canada, and Europe. Our aim was to sequence its genome and compare it with those of other strains of S aureus to try to identify genes responsible for its distinctive epidemiological and virulence properties. The community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) epidemic in the United States is largely attributable to the meteoric rise of a single clone, referred to as USA300. This strain not only spread across the United States in just a few years to become the predominant cause of staphylococcal disease, but it also appears to have increased the overall number of skin and soft-tissue infections (SSTIs), increasing the overall disease burden. Staphylococcus aureus: USA:300 is a strain of gram-positive coccus bacteria responsible for Methicillin-resistant Staphylococcus aureus (MRSA), or Staph infection in humans. This strain of S. aureus is resistant to β-lactam antibiotics. USA300 is a hypervirulent, community-acquired, multidrug-resistant Staphylococcus aureus clone that started to spread in the United States around 17 years ago. Many studies detected it also in South America, Europe, and the Asia-Pacific region.

The 2 MRSA clones in the United States most closely associated with community outbreaks, USA400 (MW2 strain, ST1 lineage) and USA300, often contain Panton-Valentine leukocidin (PVL) genes and, more frequently, have been associated with skin and soft tissue infections.

We describe a case of a young woman who had methicillin-resistant Staphylococcus aureus USA300 clone (MRSA-USA300)-associated Lemierre's syndrome and secondary necrotizing pneumonia and cerebral infarcts. We also review 11 cases of S. aureus-associated Lemierre's syndrome reported in the literature from 1965 to 2010. Recognition of S. aureus as an emergent cause of Lemierre's syndrome informs

An outbreak of severe infectious diseases caused by methicillin-resistant Staphylococcus aureus USA300 clone among hospitalized patients and nursing staff in a tertiary care university hospital

13 Nov 2008 To the Editor: In the United States, the dissemination of a major clone of community-associated methicillin-resistant Staphylococcus aureus  12 Dec 2012 USA300 is the predominant clone of community genotype methicillin-resistant Staphylococcus aureus (CG-MRSA) in North America, and it has  19 Feb 2008 Emergence of Multidrug-Resistant, Community-Associated, Methicillin-Resistant Staphylococcus aureus Clone USA300 in Men Who Have Sex 

Staphylococcus aureus: USA:300 is a strain of gram-positive coccus bacteria responsible for Methicillin-resistant Staphylococcus aureus (MRSA), or Staph infection in humans. This strain of S. aureus is resistant to β-lactam antibiotics.

Increase of the USA300 Clone Among Community-Acquired Methicillin- Susceptible Staphylococcus aureus Causing Invasive Infections. McCaskill, Michelle L. The UK-EMRSA-15 clone (ST22-MRSA-IV PVL negative) was detected in 9.8% The two isolates of the USA300 clone were resistant to penicillin, kanamycin,  27 Sep 2019 We report a case of scrotal ulcer caused by Staphylococcus aureus clone USA300 in a 56-year-old man living with human immunodeficiency  USA300 clone is one of the highest pathogenic and global epidemic community- acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) clones and  A single clone (ET 41) accounted for 88% of cases of TSS with a female Methicillin-resistant Staphylococcus aureus USA300 Clone in a Collegiate Athlete.

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